The Administrative Office staff provides administrative and professional support to the nine-member Regional University System of Oklahoma. The Administrative Office staff works with the six regional universities to develop and distribute information the Board needs as it makes plans, sets policies, and evaluates progress and performance. The Administrative Office also monitors compliance with a wide range of Board policies and procedures and assists the Board and the universities with the implementation and evaluation of systemwide projects and initiatives.

The Board is supported by staff members in various departments. These staff members oversee the various programs, services, information and affairs of the Board of Regents of the Regional University System of Oklahoma.